This study examines the effects of the medication tolcapone among individuals who regularly drink alcohol. Participants in this study will be randomly assigned to take either tolcapone or a matched placebo for 8 days. There are 3 study visits, including 2 MRI scans, and a debriefing session. This study does not involve alcohol treatment. Interested individuals must be referred for participation by the Charleston Alcohol Research Center Clinical Intake and Assessment Core. For more information, call 792-1222 or email firstname.lastname@example.org.
This study uses magnetic resonance imaging (MRI) to compare differences in brain connectivity between people with different levels of alcohol use. The study requires two visits: a clinical interview and assessment, and a 1-hour MRI scan. Subjects must be between the ages of 21 and 35. Compensation is available for eligible subjects.