A Randomized Controlled Clinical Evaluation of the DiamondTemp™ System for the Treatment of Paroxysmal Atrial Fibrillation Save

Date Added
November 28th, 2017
PRO Number
Pro00072395
Researcher
Frank Cuoco

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Keywords
Cardiovascular, Heart
Summary

The purpose of this clinical study is to see whether a medical device called the DiamondTemp Ablation Catheter (also called the DiamondTemp Ablation System) can restore the heart to a normal heart rhythm.The DiamondTemp Ablation System being evaluated in this research study is investigational because it is not approved by the FDA for the treatment of atrial fibrillation by radiofrequency ablation. The DiamondTemp System is like systems currently being used to treat atrial fibrillation with radiofrequency ablation including the control system that participants could be randomized to.

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

AMPLATZER™ Amulet™ Left Atrial Appendage Occluder Randomized Controlled Trial Save

Date Added
November 22nd, 2016
PRO Number
Pro00060406
Researcher
Frank Cuoco

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Keywords
Cardiovascular, Heart
Summary

The purpose of the AMPLATZER Amulet Left Atrial Appendage (LAA) Occluder Trial is to find out if the Amulet device is safe and effective when compared to another LAA closure device made by another medical device company named Boston Scientific. The other device, called the WATCHMAN LAA closure device, is approved for use in the United States and many countries in Europe, Australia, and other nations. It is implanted in some patients with non-valvular atrial fibrillation to reduce the risk of stroke. The WATCHMAN device will be used as the Control device in this study.

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

aMAZE TRIAL: Left Atrial Appendage Ligation with the LARIAT+ Suture Delivery System as Adjunctive Therapy to Pulmonary Vein Isolation (PVI) for Persistent or Longstanding Persistent Atrial Fibrillation Save

Date Added
October 27th, 2015
PRO Number
Pro00046852
Researcher
Frank Cuoco

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Keywords
Cardiovascular, Heart
Summary

The study is testing the safety and effectiveness of the LARIAT device in addition to a radiofrequency ablation in patients who have atrial fibrillation longer than 7 days but less than 3 years.

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

AdaptResponse Study Save

Date Added
February 24th, 2015
PRO Number
Pro00041574
Researcher
Frank Cuoco

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Keywords
Cardiovascular
Summary

This study is being done to see if receiving electrical treatment from a cardiac resynchronization therapy (CRT) device with the AdaptivCRT (aCRT) programming feature is better than receiving electrical treatment from a CRT device with the standard method of CRT device programming in patients with heart failure. Subjects will receive an already approved CRT pacemaker or defibrillator depending on what the doctor recommends. Approximately 3000 subjects will be enrolled at up to 200 centers around the world.

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

H-FIB: Adjunctive Renal Sympathetic Denervation to Modify Hypertension as Upstream Therapy in the Treatment of Atrial Fibrillation Save

Date Added
July 9th, 2013
PRO Number
Pro00026058
Researcher
Frank Cuoco

Silhouette
Keywords
Heart, Hypertension/ High Blood Pressure
Summary

The study is examining if performing renal denervation in patients with hypertension and atrial fibrillation at the time of an atrial fibrillation ablation will improve long term success (freedom from atrial fibrillation).

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

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