Post-stroke Optimization of Walking using Explosive Resistance: Concurrent effects on Depression Save

Date Added
August 7th, 2018
PRO Number
Pro00077223
Researcher
Chris Gregory

Silhouette
Keywords
Depression, Exercise, Rehabilitation Studies, Stroke
Summary

Depression contributes directly to disability following a stroke and is the single strongest predictor of quality of life. Treatment of depressive symptoms is associated with better functional recovery and return to activities of daily living. Resistance training can effectively improve post-stroke mobility and has the potential to serve as an alternative (non-drug) anti-depressant treatment option. The purpose of this study is to assess the effects of resistance training on post-stroke depressive symptoms.

Institution
MUSC
Recruitment Contact
Landi Wilson
843-792-9013
wilsolan@musc.edu

Functional Electrical Stimulation Assisted Cycling in Persons Who Have Experienced a Stroke Save

Date Added
February 3rd, 2018
PRO Number
Pro00075399
Researcher
Chris Gregory

Silhouette
Keywords
Rehabilitation Studies, Stroke
Summary

The goal of this study is to improve FES-cycling which is a common therapy. We will test a new method of adjusting the FES intensity to maintain a constant pedaling speed. We are looking for participants 18-75 years old who experienced a stroke more than 3 months ago. The study will last a single session.

Institution
MUSC
Recruitment Contact
Landi Wilson
843-792-9013
Wilsonlan@musc.edu

Treating Depression and Enhancing Locomotor Recovery Post-stroke Save

Date Added
February 4th, 2014
PRO Number
Pro00031382
Researcher
Chris Gregory

Silhouette
Keywords
Depression, Exercise, Stroke
Summary

In this project, we will assess the effects of aerobic exercise training (AET), repetitive transcranial magnetic stimulation (rTMS) or their combination on symptoms of depression as well as walking function in persons following stroke. Both of these treatments are known to be beneficial for treating depression in individuals without stroke, though neither has been adequately studied post-stroke. Furthermore, substantive studies show that exercise improves post-stroke walking function, thus offering a way to study the effects of depression on response to rehabilitation following stroke.

Institution
MUSC
Recruitment Contact
Aaron Embry
843-792-8198
embry@musc.edu

Skeletal Muscle Plasticity As An Indicator of Functional Performance Post Stroke Save

Date Added
August 12th, 2013
PRO Number
Pro00025988
Researcher
Chris Gregory

Silhouette
Keywords
Exercise, Muscle, Stroke
Summary

Weakness on one side of the body is seen in three-quarters of individuals following stroke. Weakness in this population results from both neural and muscular factors which include, respectively, the ability of the central nervous system to activate skeletal muscle as well as the force generating capacity of the muscle. Our overall goal is to improve walking in persons post-stroke by training subjects with an intervention that specifically targets these impairments, thereby facilitating locomotor recovery.

Institution
MUSC
Recruitment Contact
Aaron Embry
843-792-8198
embry@musc.edu

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