Management of Patients Presenting with Acute Chest Pain Following Coronary Computed Tomography Angiography Save

Date Added
July 9th, 2019
PRO Number
Pro00087460
Researcher
Uwe o.p. Schoepf

List of Studies


Profiles_link
Keywords
Cardiovascular, Coronary Artery Disease
Summary

Patients who present to MUSC's Chest Pain Center with acute chest pain and have undergone coronary computerized tomography angiography or triple rule-out computed tomography imaging showing an intermediate stenosis will be prospectively selected. Consented patients will then have their clinical indicated coronary computerized tomography angiography or triple rule-out computed tomography imaging undergo an expedited computed tomography-fractional flow reserve analysis analysis. This analysis will be provided to Chest Pain Center physician of record to aid in downstream patient treatment decision making. Patients will then be followed-up at 3-months via telephone call and electronic medical records review.

Institution
MUSC
Recruitment Contact
Dante Giovagnoli
8438764922
giovagnd@musc.edu

Human Samples Biorepository Save

Date Added
August 21st, 2018
PRO Number
Pro00072807
Researcher
Federica Del monte

List of Studies

Silhouette
Keywords
Aging, Cardiovascular, Coronary Artery Disease, Genetics, Heart, Military, Sarcoidosis, Scleroderma, Transplant, Vascular
Summary

The purpose of the study is to generate a bio bank of specimens for research. We will tissue that would otherwise be discarded from clinical or surgical procedure and information from medical records. We will also collect discarded blood, urines and sputum. Collecting samples will help to better understanding the mechanisms of cardiovascular diseases, identify biomarkers for early diagnosis and to predict safety and efficacy of new therapies.

Institution
MUSC
Recruitment Contact
Federica del Monte
843-792-8397
delmonte@musc.edu

The HEART Pathway: a learning health system project, translating evidence to practice across the Carolinas Save

Date Added
October 14th, 2016
PRO Number
Pro00059813
Researcher
Christine Carr

List of Studies


Profiles_link
Keywords
Coronary Artery Disease, Heart
Summary

Current care patterns for patients with acute chest pain fail to provide optimal quality and value. To avoid missing acute
coronary syndrome (ACS), emergency physicians hospitalize >50% of patients who present to the Emergency Department with
chest pain. However, s success with the HEART Pathway, the next logical step is regional dissemination.
This project will leverage Carolinas Collaborative infrastructure to collect data specific to the HEART Pathway from all 4 health
systems, establishing rates of healthcare utilization and ACS outcomes for Emergency Department patients with chest pain in
the Carolinas. In addition, we will engage key stakeholders at each health system to develop an implementation strategy. This
proposal builds on our prior work and will provide pilot data essential for a larger grant application that will support rigorous
testing and implementation of the HEART Pathway across Carolinas Collaborative health systems.

Institution
MUSC
Recruitment Contact
Christine Carr
843-792-5038
carrc@musc.edu

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