Community-based intervention under nurse guidance after stroke (CINGS) phase 1 and 2 formative investigation Save

Date Added
September 2nd, 2015
PRO Number
Pro00045745
Researcher
Gayenell Magwood

List of Studies


Profiles_link
Keywords
Cardiovascular, Minorities, Stroke
Summary

This research which encompasses a relatively new area of study that uses the Ecological Model to frame investigation is significant because it will help: (a) understand how patient, family, and community level factors impact stroke recovery and account for disparities in post stroke recovery between AA and Whites; (b) engage community members (AA, Health Provider, Families) and (c) integrate this knowledge and the interplay of socio-environmental and behavioral factors so as to develop a multi-level community based intervention with community dwelling AA in the acute post-stroke recovery period. In this model of care, the nurse guides the CHW in evidence-based interventions and the CHW links with community members to deliver the interventions to individuals. It uses nurse teleHealth guidance of the CHW and home based CHW-patient training in self-management. Together they work to disseminate and integrate the successful interventions into health and community systems. These activities will complement and build upon the growing literature related to environment guided lifestyle and self -management programs and will lead to effective socio-culturally tailored stroke recovery interventions that improve long term outcomes by directly addressing factors associated with existing disparities in recovery.

Institution
MUSC
Recruitment Contact
Gayenell Magwood
8437920685
magwoodg@musc.edu

Barostim neo- Baroreflex Activation Therapy for Heart Failure Save

Date Added
May 26th, 2015
PRO Number
Pro00044328
Researcher
Adrian Van Bakel

List of Studies

Silhouette
Keywords
Cardiovascular, Heart
Summary

The purpose of this study is to show whether the Barostim Neo system is safe and works in people with heart failure. The device is designed to stimulate the body's natural cardiovascular regulators in your neck to potentially improve your heart failure condition.

Institution
MUSC
Recruitment Contact
Mariann Schulz
843-876-5009
schulzmt@musc.edu

Impella RP System HDE Save

Date Added
April 21st, 2015
PRO Number
Pro00042253
Researcher
Daniel Steinberg

List of Studies


Profiles_link
Keywords
Cardiovascular, Heart, Surgery
Summary

This is not a research study. This HDE provides for commercial use of the Impella RP System for acute right ventricular heart failure or decompensation.

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

AdaptResponse Study Save

Date Added
February 24th, 2015
PRO Number
Pro00041574
Researcher
Michael Gold

List of Studies


Profiles_link
Keywords
Cardiovascular
Summary

This study is being done to see if receiving electrical treatment from a cardiac resynchronization therapy (CRT) device with the AdaptivCRT (aCRT) programming feature is better than receiving electrical treatment from a CRT device with the standard method of CRT device programming in patients with heart failure. Subjects will receive an already approved CRT pacemaker or defibrillator depending on what the doctor recommends. Approximately 3000 subjects will be enrolled at up to 200 centers around the world.

Institution
MUSC
Recruitment Contact
Deborah Everidge
843-792-2944
adamsde@musc.edu

Novel Magnetic Resonance Imaging Techniques For Quantitative Cardiac Parametric Mapping Save

Date Added
June 20th, 2014
PRO Number
Pro00035552
Researcher
Uwe o.p. Schoepf

List of Studies


Profiles_link
Keywords
Cardiovascular, Disease Prevention, Heart
Summary

Heart disease can be detected in the hospital by Cardiac Magnetic Resonance (CMR)- a device that uses a large magnet. CMR is used to test how healthy the heart muscle is and how well the heart is pumping. We will test a new method to see how helpful it is to quickly get good pictures and if this is useful for testing the health of heart muscle in patients with heart disease.

Institution
MUSC
Recruitment Contact
Brett Harris
843 876 8497
harrisbs@musc.edu

Development of Cardiovascular MRI Approaches Save

Date Added
June 10th, 2014
PRO Number
Pro00035686
Researcher
Uwe o.p. Schoepf

List of Studies


Profiles_link
Keywords
Cardiovascular, Healthy Volunteer Studies
Summary

Disease of the blood vessels in the legs can be detected in the hospital by Magnetic Resonance Angiography (MRA)- this uses a device that acts like a large magnet. MRA is used to test how healthy the blood vessels are and if there are any blockages. We will test a new method to see how helpful it is to quickly get good pictures and if this is useful for testing the patients with disease of the blood vessels in other regions of the body.

Institution
MUSC
Recruitment Contact
Brett Harris
843 876 8497
harrisbs@musc.edu

Pharmacokinetics of Understudied Drugs Administered to Children per Standard of Care Save

Date Added
June 5th, 2012
PRO Number
Pro00016550
Researcher
Andrew Atz

List of Studies


Profiles_link
Keywords
Cardiovascular, Genetics, Heart, Pediatrics
Summary

The majority of drugs administered to children are used off label and PK studies to define appropriate dosing are lacking across pediatric age groups. Challenges associated with clinical trials in children limit the ability to conduct PK and dosing trials in this population. Studies capitalizing on standard of care procedures have proven successful in characterizing the PK of drugs used in children.

The purpose of this study is to characterize the PK of understudied drugs administered to children per standard of care as prescribed by their treating caregiver.

This study will serve as a tool to better understand drug exposure in children receiving drugs per standard of care. The data collected through this initiative will provide valuable PK and dosing information drugs in different pediatric age groups as well as special pediatric populations (i.e. obese).

Institution
MUSC
Recruitment Contact
Layla Al Sarraf
843-876-5203
alsarral@musc.edu

"Prognostic markers in postoperative acute kidney injury" Save

Date Added
October 5th, 2009
IRB Number
10497
Researcher
Joshua Lipschutz

List of Studies

Silhouette
Keywords
Cardiovascular, Heart, Kidney
Summary

Kidney failure occurring after heart failure is a serious problem leading to prolonged ICU stay, prolonged hospitalization, dialysis and death. The goal of this study is to identify patients who will develop severe kidney failure after heart surgery. Early identification of patients who will develop kidney failure after surgery will allow earlier and better treatment to prevent this complication. In this study, urine is collected after surgery and analyzed to determine the concentration of many proteins. These proteins are potential biomarkers to predict the development of kidney failure. This is a multi-center study funded by the National Institutes of Health. It is being performed at Duke University, George Washington University and the University of Tennessee. MUSC is the lead center.

Institution
MUSC
Recruitment Contact
Tim Taylor

taylortp@musc.edu

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