Multi-site study of the efficacy of speech perception training for hearing-aid users Save

Date Added
January 16th, 2015
IRB Number
20166
Researcher
Judy Dubno
Keywords
Aging, Ears, Hearing, Minorities
Summary

This project, funded by the National Institutes of Health, is recruiting participants for a multi-site study evaluating an auditory training program for people who use hearing aids. This study includes a hearing evaluation, several listening tasks, and 30 hours of participation in a computer-based speech-training program. Native English speakers between the ages of 35 and 89 who have worn hearing aids for at least the past 3 months are currently being recruited. The study requires at least 2 visits per week for a period of 12-15 weeks, scheduled at the participant’s convenience. Compensation for time will be provided and parking validated.

Institution
MUSC
Recruitment Contact
Sara Fultz
843- 792-0667
fultzs@musc.edu

Age-related Variations in Swallowing and Aspiration Risk in Veterans Save

Date Added
December 2nd, 2014
PRO Number
Pro00039550
Researcher
Kendrea Focht
Keywords
Aging, Healthy Volunteer Studies
Summary

Age-related effects on swallowing physiology co-occurring with age-related diseases impact the health and nutritional status of aging Veterans resulting in poor quality of life and high cost of care burden. Previous studies have provided low-level evidence for potentially multiple age-related changes in swallowing function. The immediate project goal will uncover the normal variation in swallowing behavior that occurs with normal aging and incorporates a quantitative approach for measurement of swallowing observations obtained from modified barium swallow examinations. Eligible participants will undergo a modified barium swallow study, which is a continuous X-ray that records while you eat and drink. Additionally, each participant will complete three brief questionnaires related to overall general health and swallowing. To be included in the study, you must have no current or history of swallowing disorder (dysphagia), must be able to eat regular solids and drink all liquids, and must not have a disease/condition that may impact swallowing (such as a stroke, Parkinson's disease, COPD, head and neck cancer, etc.). Study is completed at the VA and is a one-time visit lasting approximately 30 minutes.

Institution
MUSC
Recruitment Contact
Kendrea Garand
843-792-6953
kendrea.focht@va.gov

Investigating the Neurobiologic Basis for Loss of Cortical Laterality in Chronic Stroke Patients Save

Date Added
February 4th, 2014
PRO Number
Pro00031250
Researcher
Colleen Hanlon
Keywords
Aging, Healthy Volunteer Studies, Stroke
Summary

Among individuals that have had a stroke, poor motor rehabilitation outcomes are often associated with elevated brain activity in the hemisphere that was not directly affected by the stroke. There are several reasons that this may be happening. The purpose of this study is to determine whether elevated brain activity in the opposite hemisphere is due to changes in brain function or brain structure.

Institution
MUSC
Recruitment Contact
William DeVries
843-792-5732
devriesw@musc.edu

The MIND Study: MR Imaging of Neurodegeneration Save

Date Added
September 18th, 2013
PRO Number
Pro00028302
Researcher
Andreana Benitez
Keywords
Aging, Alzheimers, Brain, Dementia, Geriatrics, Healthy Volunteer Studies, Memory Loss
Summary

This is a study of brain aging and Mild Cognitive Impairment (MCI). In this study, we use non-invasive brain MRI techniques and tests of memory and other thinking skills to improve the detection of brain diseases of aging at the very earliest stages. A fasting blood draw will also be performed to help clarify the contribution of blood sugar and cholesterol to brain aging. We are primarily recruiting 80 individuals ages 65-85 who have been diagnosed with Mild Cognitive Impairment (MCI) by their healthcare provider. We are also recruiting individuals ages 65-85 who are cognitively healthy and do not have any significant or unstable medical conditions. This study is sponsored by the NIH and is conducted at MUSC.

If you are interested in this study, please contact us by phone or through: http://bit.ly/MIND-study

Institution
MUSC
Recruitment Contact
Dana Szeles
(843) 876-2475
szeles@musc.edu

Physician Order for Scope of Treatment (POST): PILOT STUDY Save

Date Added
August 6th, 2013
PRO Number
Pro00022252
Researcher
Walter Limehouse
Keywords
Aging, Alzheimers, Cancer, Dementia, Ethnicity and Disease, Geriatrics, Heart, HIV / AIDS, Infectious Diseases, Kidney, Liver, Men's Health, Minorities, Nervous System, Pulmonary, Rare Diseases, Women's Health
Summary

South Carolina Coalition for Care of Serious Illness (SCC CSI) sponsors development of Physician Orders for Scope of Treatment (POST) in South Carolina. The SC POST follows the national POLST (www. polst.org) paradigm creating an advance treatment planning physician order that migrates as valid across institutional boundaries: from physician office, to home/nursing home/hospice to EMS to hospital emergency/inpatient services. The POST form encourages a conversation between a physician and the patient regarding treatment options available to seriously ill patients for whom death within a year would not be a surprise. These choices primarily include whether to attempt cardiopulmonary resuscitation in the event of cardiac or pulmonary arrest or not (a ?DNR? or ?Allow Natural Death? order) and whether during acute illness to provide full treatment including endotracheal intubation and intensive care, supportive treatment such as noninvasive ventilation and no intensive care, or comfort care only. The Charleston and Greenville areas will pilot POST. Investigators by area will survey providers completing POST documents for patients or treating patients with POST about the utility of this form and how use of the form affected their patient's treatment. A chart reviews of patients presenting with a POST form to a hospital emergency or inpatient unit will address whether providers respected patient treatment choices. SCC CSI plans to publish the results of the pilot in appropriate journals and present the results at medical meetings and to interested persons. The results of the study may provide the supporting documentation for subsequent legislation supporting POST. POST represents a coordinated statement of a seriously ill patient?s treatment choices to be honored across multiple treatment settings.

Institution
MUSC
Recruitment Contact
Walter Limehouse
792-9705
limehouw@musc.edu

Quantifying Normal Swallow Physiology across the Adult Lifespan Save

Date Added
October 4th, 2011
PRO Number
Pro00011566
Researcher
Kendrea Focht
Keywords
Aging, Healthy Volunteer Studies, Minorities
Summary

This study will involve 280 healthy adult participants. We are currently recruiting males 40 years and older and females 60 years and older. Eligible participants include those without history of head and neck cancer, without history of neurological disease (e.g., stroke, Parkinson's disease, etc), without history or chronic obstructive pulmonary disease (COPD), and without history of thyroid, carotid or spine surgery where the surgeon went through the front of your neck. Study is a one-time visit lasting less than 30 minutes, and compensation for time and travel is provided. Study procedures involve filling out 2 brief questionnaires related to swallowing and overall health. Additionally, you will be required to swallow 12 times where a continuous X-ray will be used to evaluate your swallowing function. This study is non-invasive.

Institution
MUSC
Recruitment Contact
Kendrea Garand
843-792-6953
focht@musc.edu

Experimental and Clinical Studies of Presbyacusis Save

Date Added
October 5th, 2009
IRB Number
E-607R
Researcher
Judy Dubno
Keywords
Aging, Brain, Ears, Geriatrics, Healthy Volunteer Studies, Hearing, Minorities
Summary

This project, funded by the National Institutes of Health, is being conducted to determine the effects of aging on hearing, understanding speech, and brain functions. This study will provide a scientific basis for diagnosis, rehabilitation and prevention of hearing loss due to aging. Volunteers who meet the eligibility requirements may enroll in this study, which will include measurements of hearing, making listening judgments of sounds, behavioral tasks, questionnaires, and MRI scanning of the brain. Participants 60 years of age and older with normal hearing or hearing loss are currently being recruited. Three visits of 2-3 hours each are required and scheduling is flexible.

Institution
MUSC
Recruitment Contact
Amanda Maxwell
843-792-5916
maxwelam@musc.edu

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