A Geriatric Assessment Intervention for Patients Aged 70 and Over Receiving Chemotherapy or Similar Agents for Cancer: Reducing Toxicity in Older Patients Save

Date Added
January 21st, 2015
PRO Number
Pro00041289
Researcher
James Bearden
Keywords
Aging, Cancer, Education, Non-interventional
Summary

A majority of patients diagnosed with cancer are over age 65, yet most cancer treatments are developed in a younger population. Older cancer patients are more likely to experience side effects. There is no standard way to treat chemotherapy side effects in older patients. A Geriatric Assessment (GA) can be used to predict who is at risk for side effects but there is no standard way to decrease this risk. Also, there is not agreement on how information from a GA can be used to develop ways to prevent or treat side effects.

The purpose of this study is to find out if the GA can help improve and develop a standard approach for reducing and/or preventing chemotherapy side effects in older cancer patients. The GA is intended to determine an older patient's level of independence taking into account health conditions, physical performance (walking, leg strength, and balance), nutrition, social support and memory. Several tests as well as questionnaires are used. The combined results establish what is called a patient's functional age, which may be quite different from the actual age. Functional age can help better predict a patient's tolerance of and likely response to cancer treatments as well as provide other important age-related information not routinely captured by cancer doctors. If you decide to participate in this study, you will receive the GA.

Institution
Spartanburg
Recruitment Contact
Clinical Research Department
1-800-486-5941
SurvivorshipProgram@gibbscc.org

Investigating the Neurobiologic Basis for Loss of Cortical Laterality in Chronic Stroke Patients Save

Date Added
February 4th, 2014
PRO Number
Pro00031250
Researcher
Colleen Hanlon

Silhouette
Keywords
Aging, Healthy Volunteer Studies, Stroke
Summary

Among individuals that have had a stroke, poor motor rehabilitation outcomes are often associated with elevated brain activity in the hemisphere that was not directly affected by the stroke. There are several reasons that this may be happening. The purpose of this study is to determine whether elevated brain activity in the opposite hemisphere is due to changes in brain function or brain structure.

Institution
MUSC
Recruitment Contact
William DeVries
843-792-5732
devriesw@musc.edu

The MIND Study: MR Imaging of Neurodegeneration Save

Date Added
September 18th, 2013
PRO Number
Pro00028302
Researcher
Andreana Benitez

Silhouette
Keywords
Aging, Alzheimers, Brain, Dementia, Geriatrics, Healthy Volunteer Studies, Memory Loss
Summary

This is a study of brain aging and Mild Cognitive Impairment (MCI). In this study, we use non-invasive brain MRI techniques and tests of memory and other thinking skills to improve the detection of brain diseases of aging at the very earliest stages. A fasting blood draw will also be performed to help clarify the contribution of blood sugar and cholesterol to brain aging. We are primarily recruiting 80 individuals ages 65-85 who have been diagnosed with Mild Cognitive Impairment (MCI) by their healthcare provider. We are also recruiting individuals ages 65-85 who are cognitively healthy and do not have any significant or unstable medical conditions. This study is sponsored by the NIH and is conducted at MUSC.

If you are interested in this study, please contact us by phone or through: http://bit.ly/MIND-study

Institution
MUSC
Recruitment Contact
Katrina Madden
(843) 876-2475
maddenka@musc.edu

Quantifying Normal Swallow Physiology across the Adult Lifespan Save

Date Added
October 4th, 2011
PRO Number
Pro00011566
Researcher
Ashli O'rourke

Silhouette
Keywords
Aging, Healthy Volunteer Studies, Minorities
Summary

This study will involve 280 healthy adult participants. We are currently recruiting males 40 years and older and females 60 years and older. Eligible participants include those without history of head and neck cancer, without history of neurological disease (e.g., stroke, Parkinson's disease, etc), without history or chronic obstructive pulmonary disease (COPD), and without history of thyroid, carotid or spine surgery where the surgeon went through the front of your neck. Study is a one-time visit lasting less than 30 minutes, and compensation for time and travel is provided. Study procedures involve filling out 2 brief questionnaires related to swallowing and overall health. Additionally, you will be required to swallow 12 times where a continuous X-ray will be used to evaluate your swallowing function. This study is non-invasive.

Institution
MUSC
Recruitment Contact
Kendrea Garand
843-792-6953
focht@musc.edu

A Multi-Center Randomized Placebo-Contolled Clinical Trial Study of Citalopram for the treatment of Agitation in Alzheimer's Disease (CITAD) Save

Date Added
October 5th, 2009
IRB Number
18350
Researcher
Jacobo Mintzer

Silhouette
Keywords
Aging, Alzheimers, Anxiety, Brain, Dementia, Geriatrics, Memory Loss, Mental Health
Summary

This study is designed to examine the effects and safety of citalopram in patients with Alzheimer's disease experiencing agitation or emotional disturbance. This study is 9 weeks long. In order to participate in this study, you must be at least 45 years old, have Alzheimer's disease and experience agitation. Participants cannot have depression. Participants may stay on approved memory medications for Alzheimer's disease.

Institution
MUSC
Recruitment Contact
Marie Corbin
843-740-1592
corbinm@musc.edu

Experimental and Clinical Studies of Presbyacusis Save

Date Added
October 5th, 2009
IRB Number
E-607R
Researcher
Judy Dubno

Silhouette
Keywords
Aging, Brain, Ears, Geriatrics, Healthy Volunteer Studies, Hearing, Minorities
Summary

This project, funded by the National Institutes of Health, is being conducted to determine the effects of aging on hearing, understanding speech, and brain functions. This study will provide a scientific basis for diagnosis, rehabilitation and prevention of hearing loss due to aging. Volunteers who meet the eligibility requirements may enroll in this study, which will include measurements of hearing, making listening judgments of sounds, behavioral tasks, questionnaires, and MRI scanning of the brain. Participants 60 years of age and older with normal hearing or hearing loss are currently being recruited. Three visits of 2-3 hours each are required and scheduling is flexible.

Institution
MUSC
Recruitment Contact
Jessica McCay
843-792-5916
mccayj@musc.edu

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